How to pick a problem. Today in Cell. 1/53
cell.com/cell/fulltext/…

Another trial showing no benefit of early treatment of a PDA

Selection, definition, etc. … yes, know the arguments that will come … but at some point shouldn’t trial evidence >> physiologic rationale (without evidence of benefit on outcomes)

nejm.org/doi/full/10.10…

#neoEBM

Fascinating, award-winning talk from Stanford Neonatology fellow Danielle Perez Sharp on NIRS’ association with coarctation severity! #NIRSnerds #wspr2024 #neoTwitter

Time to open the DOOR neonatalresearch.org/2024/01/17/tim…
#NeonatalResearch
#NeoEBM
#NeoMastodon
Join me in the nicuverse.org

Interesting!....Single-cell analysis of prenatal and postnatal human cortical development | Science science.org/doi/10.1126/sc…

Pretty good math. I had come up with 400 deaths annually. That now makes 2 deaths due to probiotics over a decade? It’s also not just mortality. Surgical NEC has significant impact on NDI. Evidence would suggest as bad as grade IV IVH

Our new lipidomics paper is out--very cool, but understudied molecules. nature.com/articles/s4225…

Stanford Neonatology Stanford Pediatrics Congratulations Anca M. Pasca, MD !! 🥳🥳

📄 This paper from UI Stead Family Department of Pediatrics not only outlines their hemodynamic screening approach to PDA in infants ≤ 26 wks but also reports how that strategy reduced rates of death or severe #BPD by 50% and improved survival free of severe morbidities to 73% in 22-23 wks infants!…

Our new microsampling paper is out for remote sampling. Can measure 1000s of analyses. Very excited about it.
rdcu.be/c3M4n

Join our Stanford Metabolic Health Center Annual Symposium on Thursday, March 2nd, 2023
Speakers include Michael Snyder, PhD Dr. Michael Snyder, Dr. Segal, Dr. Aagaard, Dr. Wernimont , Dr. Aghaeepour , Dr. Subramaniam , and Dr. Long
lnkd.in/gai2D9mR
#snyderlab #genetics #health

Don’t miss this excellent opportunity! FREE grant writing workshop by Sarah Dobson. And for more career resources for scientists check out our website edgeforscholars.vumc.org Edge for Scholars Local

Wow this is ground breaking for moms! However the analysis for neonates was completely useless... 1/n

Azithromycin to Prevent Sepsis or Death in Women Planning a Vaginal Birth | NEJM nejm.org/doi/full/10.10…

👉Important message: a striking lack of correlation between #pathway abundance🦠and plasma #metabolite levels🩸(cohort, n=1055), emphasising that gene abundances in gut metagenomes are not (on their own) a useful predictor of plasma metabolic outputs.
nature.com/articles/s4158…

Great occasion for my 1st tweet! Proud contributor to this nature perspective on the ongoing debate questioning a fetal #microbiome . With 46 experts in #microbiome #science and related disciplines, we assess the evidence. The answer, an unambiguous ‘No’ bit.ly/3XF4ePg

Looking forward to speaking at the Metabolic Health Center Symposium in March. Register here: med.stanford.edu/metabolichealt…

Stanford Anesthesiology Stanford Children's Stanford Neonatology Stanford Pediatrics Stanford Maternal & Child Health Research Inst. Stanford Immunology StanfordDBDS Burroughs Wellcome Fund March of Dimes Burroughs Wellcome Fund

Thrilled to share NEJM case study describing in utero enzyme replacement treatment of a fetus with infantile-onset Pompe—a lysosomal storage disease. Wonderful collaborators CHEO Ottawa Duke Health & co-lead authors Drs. Jennifer L. Cohen & Pranesh Chakraborty🧵bit.ly/3DNcbcg

Wow... From Nov 1st @nature is publishing reviewer reports and author responses for ALL research articles. Do you think it's a good step?
#OpenScience
go.nature.com/3NlP8Ke

Yes, and the title of my invited editorial. It was an honor to participate in the conversation in NEJM.
Parenteral Protein in Extremely Preterm Infants — More Is Not Better | NEJM nejm.org/doi/full/10.10…

I’m pleased to announce that I’m the new #researchchair @TecanNeo. Looking for person with expertise in #QI to help me, esp with #QI summerschool (created by Jenny Koo, MD, FAAP!) DM if interested.