PHARM.Dabbler(@PharmDabbler) 's Twitter Profile Photo

$PDSB 2024 Catalysts

- Initiate pivotal study in HNSCC: PDS01ADC + Versamune® HPV + pembrolizumab Triple Combo - 2024

- Update on regulatory confirmation of potentially registrational study - Q3-2024

- File IND for Versamune MUC1 Triple Combo Ph 1/2 study in t/m colorectal…

$PDSB 2024 Catalysts

- Initiate pivotal study in HNSCC: PDS01ADC + Versamune® HPV + pembrolizumab Triple Combo - 2024

- Update on regulatory confirmation of potentially registrational study - Q3-2024

-  File IND for Versamune MUC1 Triple Combo Ph 1/2 study in t/m colorectal…
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Peter Davis(@peter_brit) 's Twitter Profile Photo

$nwbo

Another Merck Phase 3 failure -
- KEYNOTE-B21 Trial Evaluating KEYTRUDA® (pembrolizumab)

'KEYTRUDA, Merck’s anti-PD-1 therapy, in combination with chemotherapy as adjuvant treatment, with or without radiotherapy, did not meet its primary endpoint of…

#dcvax $nwbo #gbm 

Another Merck Phase 3 failure - 
 - KEYNOTE-B21 Trial Evaluating KEYTRUDA® (pembrolizumab)

'KEYTRUDA, Merck’s anti-PD-1 therapy, in combination with chemotherapy as adjuvant treatment, with or without radiotherapy, did not meet its primary endpoint of…
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InHonourOfThomasWPhelps(@ConradEnge98050) 's Twitter Profile Photo

Health Stocks News $MRK another poor trial.
Large synergistic effect anti-PD1 + ITK inhibitor $CRVS increases murine survival from 25% to 90%!
ITKi reverses T-cell exhaustion

$CRVS upcoming solid tumor mono/combo! 2024/25

twitter.com/ConradEnge9805…

@health_stocks $MRK another poor #Keynote #Keytruda trial.
Large synergistic effect anti-PD1 #pembrolizumab + ITK inhibitor $CRVS #soquelitinib increases murine survival from 25% to 90%!
ITKi reverses T-cell exhaustion

$CRVS upcoming solid tumor mono/combo! 2024/25

twitter.com/ConradEnge9805…
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GI Oncology Now(@GiOncNow) 's Twitter Profile Photo

🔎 Following the KEYNOTE-811 trial, Merck announced that with and chemotherapy may benefit patients with HER2-positive, locally advanced, unresectable or metastatic gastric or GEJ adenocarcinoma.

👉 Learn more: buff.ly/3wqH5YA

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ThinkSabio.com(@think_sabio) 's Twitter Profile Photo

$SPX $SPY $XBI $QQQ $IWM

$CGEM: $28.75
Live Cash: $382.59M

$19.27 to $29.35 Diff :$10.08
* Consistently going up since 3 weeks with 62% Gain

Upcoming catalyst:
Drug: CLN-619 - (MICA) monotherapy and in combination with pembrolizumab
Date:…

#ThinkSabio #Trendingstock $SPX $SPY $XBI $QQQ $IWM #Markets 

$CGEM: $28.75
Live Cash: $382.59M
 
$19.27 to $29.35 Diff :$10.08
* Consistently going up since 3 weeks with 62% Gain 

Upcoming catalyst:
Drug: CLN-619 - (MICA) monotherapy and in combination with pembrolizumab
Date:…
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OncLive.com(@OncLive) 's Twitter Profile Photo

Treatment with eftilagimod alpha plus standard-of-care radiotherapy and pembrolizumab was shown to be well tolerated and led to encouraging initial efficacy data in patients with soft tissue sarcoma. onclive.com/view/eftilagim…

Treatment with eftilagimod alpha plus standard-of-care radiotherapy and pembrolizumab was shown to be well tolerated and led to encouraging initial efficacy data in patients with soft tissue sarcoma.  #oncology #sarcoma onclive.com/view/eftilagim…
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Dr Amol Akhade(@SuyogCancer) 's Twitter Profile Photo

Why pembrolizumab does not work along with cisplatin based CTRT in head neck cancer ( keynote 412 ) But same pembrolizumab works in cervical cancer with CTRT ( Keynote A18 ) . Perspective by Dr Voortman for head neck cancer part in The Lancet Oncology What can be reasons? Different…

Why pembrolizumab does not work along with cisplatin based CTRT in head neck cancer ( keynote 412 )  But same pembrolizumab  works in cervical cancer with CTRT ( Keynote A18 ) . Perspective by Dr Voortman for head neck cancer part in @TheLancetOncol What can be reasons? Different…
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Health Stocks News(@health_stocks) 's Twitter Profile Photo

Merck Provides Update on Phase 3 KEYNOTE-B21 Trial Evaluating KEYTRUDA® (pembrolizumab) Plus Chemotherapy, With or Without Radiotherapy, for Patients With Newly Diagnosed, High-Risk Endometrial Cancer After Surgery With Curative Intent $MRK healthstockshub.com/news/nyse/mrk/…

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Elisa Agostinetto(@ElisaAgostinett) 's Twitter Profile Photo

The long and winding road to biomarkers for immunotherapy🏔️

A comprehensive analysis led by Laurence Buisseret of samples from pts with TNBC treated with pembrolizumab highlights the huge heterogeneity among TNBCs

Now out in ESMO Open ⬇️

OncoAlert

authors.elsevier.com/sd/article/S20…

The long and winding road to biomarkers for immunotherapy🏔️

A comprehensive analysis led by @LauBuisseret of samples from pts with TNBC treated with pembrolizumab highlights the huge heterogeneity among TNBCs 

Now out in @ESMO_Open ⬇️

@OncoAlert 

authors.elsevier.com/sd/article/S20…
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Sociedad Argentina de Medicina (SAM)(@MedicinaSAM) 's Twitter Profile Photo

📢 Supervivencia global con pembrolizumab adyuvante en el de células renales.
▶️El adyuvante se asoció con una mejora clínicamente significativa en la supervivencia general, comparado con placebo, entre las🤼 mayor riesgo de recurrencia.‼️…

📢 Supervivencia global con pembrolizumab adyuvante en el #carcinoma de células renales.
▶️El #pembrolizumab adyuvante se asoció con una mejora clínicamente significativa en la supervivencia general, comparado con placebo, entre las🤼 mayor riesgo de recurrencia.‼️…
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イシヤク | 医師向け薬剤比較アプリ(@IshiyakuApp) 's Twitter Profile Photo

【呼吸器内科】
ASCO2023_肺がんまとめ

主要演題テーマ
・術前におけるニボルマブの根治手術有無による有効性の違いは?
・術前におけるPembrolizumab+Ramucirumabの有効性と安全性は?
・術前におけるオシメルチニ

▼続きはAntaa Slideで
slide.antaa.jp/article/view/6…

【呼吸器内科】
ASCO2023_肺がんまとめ

主要演題テーマ
・術前におけるニボルマブの根治手術有無による有効性の違いは?
・術前におけるPembrolizumab+Ramucirumabの有効性と安全性は?
・術前におけるオシメルチニ

▼続きはAntaa Slideで
slide.antaa.jp/article/view/6…
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Clinical Lung Cancer(@ClinicalLung) 's Twitter Profile Photo

Check an article on patients who completed two years of for advanced NSCLC, highlighting high rates of KRAS mutation & PD-L1 expression, and a subset with brain metastases and treated oligoprogression.

Full article: bit.ly/3Qz1FNa

Check an article on patients who completed two years of #pembrolizumab for advanced NSCLC, highlighting high rates of KRAS mutation & PD-L1 expression, and a subset with brain metastases and treated oligoprogression.

Full article: bit.ly/3Qz1FNa
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OncLive.com(@OncLive) 's Twitter Profile Photo

Frontline eftilagimod alpha plus pembrolizumab generated responses in patients with recurrent or metastatic HNSCC with negative PD-L1 expression in cohort B of the phase 2b KEYNOTE-PNC-34/TACTI-003 trial. onclive.com/view/eftilagim…

Frontline eftilagimod alpha plus pembrolizumab generated responses in patients with recurrent or metastatic HNSCC with negative PD-L1 expression in cohort B of the phase 2b KEYNOTE-PNC-34/TACTI-003 trial. #hncsm #oncology onclive.com/view/eftilagim…
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Ezra Cohen(@DrEzraCohen) 's Twitter Profile Photo

We need to change the paradigm in LA-HNSCC. Adding anti-PD1/PDL1 concurrently or adjuvantly has not worked. I think the solution will come with better biomarkers, changing radiation dosing, and rationally applied therapy sequencing. thelancet.com/journals/lanon…

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CCTG(@CDNCancerTrials) 's Twitter Profile Photo

Thank you to Dr. Penny Bradbury Princess Margaret Cancer Centre for presenting the phase III IND227 results - Pembrolizumab in Patients with Advanced Malignant Pleural Mesothelioma at the plenary.

Thank you to Dr. Penny Bradbury @pmcancercentre for presenting the phase III IND227 results - Pembrolizumab in Patients with Advanced Malignant Pleural Mesothelioma at the #CCTG2024 plenary.
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